This large building has a rectangular floor and four courtyards defined by a cruciform layout of two large corridors used as infirmaries. The main façade has two parts, with Doric and ionic frames, the upper part being more adorned with a great marble doorway crowned with the coat of arms of the Cinco Llagas foundation, at the side of which are the coats of arms of the founders. The chapel, designed by Hernán Ruiz en 1560, is very representative of his style of work. In order to comprehend the importance, we must go back to 1500, the year in which Catalina de Ribera obtained the papal bull which allowed one of the best known and popular works of charity in 16th century Seville. This work was continued and extended by her son, Don Fadrique Enriquez de Ribera, Marquis of Tarifa, until his death in 1539. A year later, by means of last will/testament, the foundation passed into the hands of the priories of Santa Maria de las Cuevas and the monasteries of San Jerónimo de Buenavista and San Isidoro del Campo; and as such became open to public competition for the construction of a majestic building in the proximity of the Macarena gateway. Tenders were received from prestigious architects of the time and finally granted to Martin Gainza. Gainza began work began in 1546, continued up to his death, and was succeeded by Hernán Ruiz, who was similarly succeeded by the Neapolitan Benvenuto Tortello in1570 and set to work in 1572 on Aresenio de Maeda's project. The hospital was functional until it was forced to close due to its deteriorating state. The building was restored and is currently used as the seat of the Andalusian Parliament.
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